By H. Arnouk
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Additional info for Advancements in Tumor Immunotherapy, Cancer Vaccines
However, docetaxel is cell-cycle specific, which means that it is cytotoxic to all dividing cells and not just tumor cells. Patients who take docetaxel are likely to experience neutropenia, anemia, neuropathy, alopecia, and nail damage. Docetaxel-based therapy is not a cure as some patients fail therapy. Because of this, therapeutic strategies that offer a more favorable toxicity profile while providing more effective treatments are needed for the management of disease progression. Prostate cancer vaccines have the ability to target tumor-specific antigens while leaving healthy cells intact (Vieweg, Dannul, 2005).
2007). Plasmid DNA vaccine encoding prostatic acid phosphatase is effective in eliciting autologous antigen-specific CD8+ T cells. Cancer Immunolology, Immunotherapy, Vol. 56, No. 6, (June 2007), pp. , & Tannir N. (2008). Vaccination of metastatic renal cell carcionma patients with autologous tumour-derived vitespen vaccin : clinical findings. British Journal of Cancer, Vol. 98, (March 2008), pp. L. R. (2010). Overall survival analysis of a phase II randomized controlled trial of a poxviral-based PSA-targeted immunotherapy in metastatic castration-resistant prostate cancer.
Immunization of cancer patients with autologous cancer-derived heat shock protein GP96 preparations: a pilot study. International Journal of Cancer, Vol. 88, No. 2, (October 2000), pp. G. (2007). Plasmid DNA vaccine encoding prostatic acid phosphatase is effective in eliciting autologous antigen-specific CD8+ T cells. Cancer Immunolology, Immunotherapy, Vol. 56, No. 6, (June 2007), pp. , & Tannir N. (2008). Vaccination of metastatic renal cell carcionma patients with autologous tumour-derived vitespen vaccin : clinical findings.