Advances in Organometallic Chemistry, 7 by F G A Stone; Robert West

By F G A Stone; Robert West

ADVANCES ORGANOMETALLIC CHEMISTRY V 7.

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Advances in Organometallic Chemistry, 7

ADVANCES ORGANOMETALLIC CHEMISTRY V 7.

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These studies point up the long-known pronounced effect of physical properties and of structure on the toxicity of several classes of compounds. With organolead compounds, it is known that the volatile tetraethyllead is quite toxic; and even the solid organolead halides of the More Than One-Half Century of Organometallic Chemistry 31 R3PbX type have the highly disagreeable physiological property of being active sternutators. However, marked alterations in pharmacological action can be effected by variations in structure.

G. , Nobis, J. , Thirtle, J. , Yale, H. , and Yeoman, F. , J. Am. Chem. SOC. 78, 2790 (1956); and subsequent papers in this series. 26. , in “Encyclopaedia Britannica,” Vol. 16, p. 1089. Benton, London, 1966. 27. , and Schwebke, G. , Adwan. Organometal. Chem. 1,89 (1964). 28. , and Winkler, H. J. , in “Organometallic Chemistry” (H. ), p. 270. Reinhold, New York, 1960. 29. , and Wright, G. , Chem. Rew. 11, No. 3, 323 (1932). 30. , and Yale, H. , Chem. Rev. 30, No. 2, 281 (1942). 31. Ingham, R. , in “ Inorganic Polymers” (F.

In “Encyclopaedia Britannica,” Vol. 16, p. 1089. Benton, London, 1966. 27. , and Schwebke, G. , Adwan. Organometal. Chem. 1,89 (1964). 28. , and Winkler, H. J. , in “Organometallic Chemistry” (H. ), p. 270. Reinhold, New York, 1960. 29. , and Wright, G. , Chem. Rew. 11, No. 3, 323 (1932). 30. , and Yale, H. , Chem. Rev. 30, No. 2, 281 (1942). 31. Ingham, R. , in “ Inorganic Polymers” (F. G. A. Stone and W. A. G. ), p. 321. Academic Press, New York, 1962. 32. Ingham, R. , in “Introduction to Organotin Chemistry” (A.

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