By Gretchen M Lentz MD, Rogerio A. Lobo MD, David M Gershenson MD, Vern L. Katz MD
Previously edited through Drs. Droegemueller, Stenchever, Mishell & Herbst - this depended on and confirmed reference offers entire, well timed, and simple entry to very important info at the clinical and surgical concerns affecting modern-day day-by-day gynecology perform. that includes the clean views of 4 new editors, besides new participants, the textual content deals useful, in-depth coverage...helpful illustrations - many new to this edition...and clinically orientated guidance...page after web page! Plus, entry the whole contents on-line, absolutely searchable at www.compgyn.com - so that you can locate quickly solutions from an location.Access cutting-edge assistance at the newest minimally invasive surgical techniques...the most recent purposes in diagnostic and interventional ultrasound...and many different crucial elements of latest perform. entry clean perform views from 4 new editors and new participants. successfully deal with the emotional facets of the distinctiveness with targeted new chapters masking rape * incest * and family violence, between others. Diagnose stipulations appropriately with the visible relief of approximately 1,000 illustrations - together with greater than a hundred new full-color photos.Quickly locate the knowledge you would like with elementary good points together with key phrases, key issues, and using colour throughout.Exponentially improve your scientific reference strength with entry to the whole contents on-line - absolutely searchable - in addition to all the illustrations to be used in digital displays. stopover at www.compgyn.com for details.Presents the paintings of 4 new affiliate editors and plenty of new participants who provide clean perform perspectives.Includes precise new chapters protecting rape · incest · family violence · and different hugely emotional elements of the specialty.Features greater than a hundred new full-color pictures that assist you determine lesions and interpret pathologic findings.Provides elevated fabric on menopause, reflecting the ever-increasing getting older sufferer inhabitants.
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Extra info for Comprehensive Gynecology
Intron. Noncoding region of a gene. A gene will have many introns intervening between the coding regions (exons). Inversion. A condition occurring when a chromosome suffers two breaks with a 180° rotation of the fragments. If the centromere is involved in the inversion, the condition is called a pericentric inversion. If the centromere is not included, it is called a paracentric inversion. Isochromosome. An abnormal chromosome that is produced by a transverse split instead of the usual longitudinal split of the centromere.
RFLPs are generated using restriction endonucleases and can indirectly identify mutations in a gene that is near a polymorphic site. Ribonucleic Acid (RNA). A single-helix nuclear protein that serves several purposes in the cell. It is composed of a sugar (ribose), a phosphate, and a purine or pyrimidine base. Translocation. The transfer of a segment of chromosome material from one chromosome to another. A number of illnesses and conditions have a genetic basis. In some cases the problem arises from a single-point mutation within a gene, whereas others may involve changes in multiple genes or in an interreaction of genes and environmental factors.
This powerful tool can provide a “molecular fingerprint” of an individual's disease and is referred to as gene expression profiling (GEP). Molecular differences revealed by gene expression patterns of individuals with the same condition, such as, type II diabetes, may give insights into the mechanisms contributing to the disease, to its prognosis, and to more specific treatments, such as individualized drug therapy. The use of microarrays have expanded into areas of genetic diagnosis, in which, simultaneous screening for many different genetic conditions in an individual is now possible.